Fluorine Labeling as a Versatile Tool for Probing Nucleic Acid Folding and Interactions by NMR Spectroscopy

Varování

Publikace nespadá pod Pedagogickou fakultu, ale pod Středoevropský technologický institut. Oficiální stránka publikace je na webu muni.cz.

Autoři	ZLÍNSKÁ Vladimíra MATOUSEK Vaclav TRANTÍREK Lukáš RIGO Riccardo
Rok publikování	2022
Druh	Článek v odborném periodiku
Časopis / Zdroj	ALDRICHIMICA ACTA
Fakulta / Pracoviště MU	Středoevropský technologický institut
Citace
www	https://www.sigmaaldrich.com/CZ/en/collections/aldrichimica-acta
Klíčová slova	F-19 NMR spectroscopy; F-19 probes; DNA; RNA; F-19-labeling approaches; nucleic acid folding; nucleic acid/small molecule interactions; nucleic acid/protein interactions; in vitro; in vivo
Popis	This mini-review provides an overview of approaches to F-19-labeling of nucleic acids. A special attention is paid to applications of F-19-labeled nucleic acids to resolve their polymorphism and characterize their folding and interactions with ligands and proteins in vitro and in living cells by using NMR spectroscopy.
Související projekty:	Atomically resolved in vivo NMR spectroscopy as a novel tool for biological testing of therapeutically important genomic non-canonical DNA targets and their interactions with drugs in phenotypically diversified cancer cells. MSCAfellow4@MUNI