Hyperintenzivní léze reagující na steroidy u pacienta s Creutzfeldt-Jakobovou nemocí

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Title in English	Steroid-Responsive Hyperintense Lesions in a Patient with Creutzfeldt-Jakob Disease
Authors	SHEARDOVÁ Kateřina MATĚJ R. REKTOROVÁ Irena
Year of publication	2010
Type	Article in Periodical
Magazine / Source	Ceska a slovenska neurologie a neurochirurgie
MU Faculty or unit	Faculty of Medicine
Citation
Field	Neurology, neurosurgery, neurosciences
Keywords	Creutzfeldt-Jakob disease; magnetic resonance imaging; corticosteroids
Description	Abstract: Typical hyperintense changes in the striata and cerebral cortices on T2-weighted (T2W), fluid-attenuated inversion recovery (FLAIR), and diffusion-weighted imaging (DWI) have been described in patients with Creutzfeldt-Jakob disease (CJD). We report the case of a 71-year-old woman with a definite autopsy-proven diagnosis of sporadic CJD Heidenhain variant with T2W and FLAIR hyperintense lesions in parietal and occipital cortex bilaterally on MRI, regressing after steroid administration despite progression of the disease.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.