Vliv memantinu a jeho kombinace s fluoxetinem na aktivitu CYP2D2 u potkana

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Title in English	The influence of memantine and its combination with fluoxetine on the activity of CYP2D2 in rats
Authors	ZENDULKA Ondřej ZAHRADNÍKOVÁ Lucia JUŘICA Jan ŠULCOVÁ Alexandra
Year of publication	2009
Type	Article in Periodical
Magazine / Source	Psychiatrie
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pharmacology and pharmaceutical chemistry
Keywords	cytochrome P450; memantine; fluoxetine
Description	Memantine inhibits the metabolic activity of CYP2D2 in rats. The work compares the influence of memantine alone as well as the combination with fluoxetine.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.