Farmakokinetická interakce metamfetaminu a fluoxetinu na úrovni CYP450 2D1 v preklinickém experimentu

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Title in English	Pharmacokinetics interaction of methamphetamine and fluoxetine on metabolic activity of CYP2D1 in preclinical experiment
Authors	DOSTÁLEK Miroslav SLÍVA Jiří
Year of publication	2002
Type	Article in Proceedings
Conference	46. Studentská vědecká konference
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pharmacology and pharmaceutical chemistry
Keywords	izolated perfused liver;methamphetamine; fluoxetine; CYP2D1
Description	The aim of the present study was to investigate the influence of fluoxetine on the metabolic activity of CYP2D1/2 and CYP3A1/2 in the isolated perfused liver of rats pretreated by methamphetamine.
Related projects:	Plasticity of Regulatory Mechanisms of the Central Nervous Systems