Influence of pharmacological manipulation with 5-HT1A receptor subtype on social behaviour in mice

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Authors	NOVÁKOVÁ Jana VINKLEROVÁ Jana ŠULCOVÁ Alexandra
Year of publication	2002
Type	Article in Periodical
Magazine / Source	Homeostasis
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pharmacology and pharmaceutical chemistry
Keywords	5-HT1A receptor ligands; agonistic behaviour; mice
Description	The study investigated the effect of selective 5-HT1A receptor ligand agonist on paired social interactions in singly-housed male mice with non-aggressive group-housed partners which is known as a model of agonistic behaviour. From our results, there is the evidence that selective agonistic manipulation with 5-HT1A receptor subtype possesses marked antiaggressive and less pronounced anxiolytic activity.
Related projects:	Plasticity of Regulatory Mechanisms of the Central Nervous Systems