Úloha adenosinového receptoru A2 v modulaci sociálního chování myší.
| Title in English | The role of adenosine A2 receptors in modulation of social behaviour in mice |
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| Authors | |
| Year of publication | 2002 |
| Type | Article in Periodical |
| Magazine / Source | Psychiatrie |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | adenosine A2 receptors - caffeine - CGS 21680 - social behaviour - mice |
| Description | Adenosine A2 receptor knock-out mice are more agressive. In the present study caffeine, the selective antagonist at A2A receptors increased occurence of aggressive acts in male mice, while agonist of A1/A2A receptors CGS 21680 their aggressivity inhibited. The results confirm a suggestion that A2 receptors are involved in regulation of behaviour. |
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