Imunohistochemická analýza retrakční kapsy pars tensa ušního bubínku u dětí

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Title in English	Immunohistochemical Analysis of Pars Tensa Retraction Pocket in Children
Authors	URÍK Milan HURNÍK P. ŽIAK D. MACHAČ Josef ŠLAPÁK Ivo MOTYKA O. DVOŘÁČKOVÁ J. JABANDŽIEV Petr
Year of publication	2017
Type	Article in Periodical
Magazine / Source	Otorinolaryngologie a foniatrie
MU Faculty or unit	Faculty of Medicine
Citation
Field	ORL, ophthalmology, stomatology
Keywords	retraction pocket; immunohistochemical analysis; cholesteatoma; childhood
Description	Introduction: Immunohistochemical analysis of pars tensa retraction pocket in children. Identification of signs typical for cholesteatoma and to support the retraction theory of cholesteatoma. Methods: Standard process of immunohistochemistry of retraction pockets. For immunohistochemistry we used CD45 LCA (Leukocyte common antigen), CD31 (platelet and endothelial cell adhesion molecule), D2-40 (podoplanin - lymphatic vessels) MMP9 (matrix meta-lloproteinase 9 - degradation of extracellular matrix) Ki67 (nuclear proliferation).
Related projects:	Ztráta sluchu v dětském věku - příčiny, diagnostika, možnosti rehabilitace.